4jvs

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{{STRUCTURE_4jvs| PDB=4jvs | SCENE= }}
 
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===Crystal structure of LepB GAP domain from Legionella drancourtii in complex with Rab1-GDP and AlF3===
 
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{{ABSTRACT_PUBMED_23588383}}
 
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==Function==
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==Crystal structure of LepB GAP domain from Legionella drancourtii in complex with Rab1-GDP and AlF3==
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[[http://www.uniprot.org/uniprot/RAB1A_HUMAN RAB1A_HUMAN]] Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.
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<StructureSection load='4jvs' size='340' side='right'caption='[[4jvs]], [[Resolution|resolution]] 2.78&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4jvs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Legionella_drancourtii_LLAP12 Legionella drancourtii LLAP12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JVS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JVS FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.783&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=AF3:ALUMINUM+FLUORIDE'>AF3</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jvs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jvs OCA], [https://pdbe.org/4jvs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jvs RCSB], [https://www.ebi.ac.uk/pdbsum/4jvs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jvs ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/G9EPL4_9GAMM G9EPL4_9GAMM]
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==About this Structure==
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==See Also==
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[[4jvs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Legionella_drancourtii_llap12 Legionella drancourtii llap12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JVS OCA].
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*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Legionella drancourtii llap12]]
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[[Category: Large Structures]]
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[[Category: Shao, F.]]
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[[Category: Legionella drancourtii LLAP12]]
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[[Category: Wang, D C.]]
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[[Category: Shao F]]
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[[Category: Yao, Q.]]
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[[Category: Wang D-C]]
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[[Category: Yu, Q.]]
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[[Category: Yao Q]]
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[[Category: Bind and hydrolyze guanosine triphosphate]]
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[[Category: Yu Q]]
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[[Category: Hydrolase activator-protein transport complex]]
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[[Category: New gap fold]]
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[[Category: Rab1 binding]]
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Current revision

Crystal structure of LepB GAP domain from Legionella drancourtii in complex with Rab1-GDP and AlF3

PDB ID 4jvs

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