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4gxl

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{{STRUCTURE_4gxl| PDB=4gxl | SCENE= }}
 
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===The crystal structure of Galectin-8 C-CRD in complex with NDP52===
 
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{{ABSTRACT_PUBMED_23386746}}
 
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==Function==
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==The crystal structure of Galectin-8 C-CRD in complex with NDP52==
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[[http://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN]] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref> [[http://www.uniprot.org/uniprot/CACO2_HUMAN CACO2_HUMAN]] May play a role in ruffle formation and actin cytoskeleton organization. Seems to negatively regulate constitutive secretion.<ref>PMID:17635994</ref>
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<StructureSection load='4gxl' size='340' side='right'caption='[[4gxl]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4gxl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GXL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.023&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gxl OCA], [https://pdbe.org/4gxl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gxl RCSB], [https://www.ebi.ac.uk/pdbsum/4gxl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gxl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref>
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==About this Structure==
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==See Also==
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[[4gxl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GXL OCA].
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*[[Galectin 3D structures|Galectin 3D structures]]
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== References ==
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==Reference==
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<references/>
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<references group="xtra"/><references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: He, C.]]
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[[Category: Large Structures]]
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[[Category: Li, F.]]
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[[Category: He C]]
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[[Category: Li, S.]]
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[[Category: Li F]]
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[[Category: Liu, Z.]]
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[[Category: Li S]]
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[[Category: Randow, F.]]
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[[Category: Liu Z]]
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[[Category: Shi, Y.]]
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[[Category: Randow F]]
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[[Category: Wandel, M P.]]
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[[Category: Shi Y]]
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[[Category: Wu, J.]]
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[[Category: Wandel MP]]
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[[Category: Carbohydrate recognition]]
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[[Category: Wu J]]
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[[Category: Ndp52]]
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[[Category: Protein binding]]
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[[Category: Protein-protein interaction]]
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Current revision

The crystal structure of Galectin-8 C-CRD in complex with NDP52

PDB ID 4gxl

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