4gec

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:28, 1 March 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_4gec| PDB=4gec | SCENE= }}
 
-
===Crystal Structure of E.coli MenH R124A Mutant===
 
-
==Function==
+
==Crystal Structure of E.coli MenH R124A Mutant==
-
[[http://www.uniprot.org/uniprot/MENH_ECOLI MENH_ECOLI]] Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro.<ref>PMID:15808744</ref> <ref>PMID:18284213</ref>
+
<StructureSection load='4gec' size='340' side='right'caption='[[4gec]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==About this Structure==
+
<table><tr><td colspan='2'>[[4gec]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GEC FirstGlance]. <br>
-
[[4gec]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GEC OCA].
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
==Reference==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gec OCA], [https://pdbe.org/4gec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gec RCSB], [https://www.ebi.ac.uk/pdbsum/4gec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gec ProSAT]</span></td></tr>
-
<references group="xtra"/><references/>
+
</table>
-
[[Category: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase]]
+
== Function ==
-
[[Category: Escherichia coli k-12]]
+
[https://www.uniprot.org/uniprot/MENH_ECOLI MENH_ECOLI] Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro.<ref>PMID:15808744</ref> <ref>PMID:18284213</ref>
-
[[Category: Baker, E N.]]
+
== References ==
-
[[Category: Guo, Z.]]
+
<references/>
-
[[Category: Jiang, M.]]
+
__TOC__
-
[[Category: Johnston, J M]]
+
</StructureSection>
-
[[Category: 2-succinyl-6-hydroxy-2]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: 4-cyclohexadiene-1-carboxylate synthase]]
+
[[Category: Large Structures]]
-
[[Category: Alpha beta hydrolase]]
+
[[Category: Baker EN]]
-
[[Category: Lyase]]
+
[[Category: Guo Z]]
-
[[Category: Menaquinone biosynthesis]]
+
[[Category: Jiang M]]
-
[[Category: Menh mutant r124a]]
+
[[Category: Johnston JM]]
-
[[Category: Mutant r124a]]
+

Current revision

Crystal Structure of E.coli MenH R124A Mutant

PDB ID 4gec

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4gec"
Personal tools