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3qgb

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{{STRUCTURE_3qgb| PDB=3qgb | SCENE= }}
 
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===Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa===
 
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{{ABSTRACT_PUBMED_21372189}}
 
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==Function==
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==Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa==
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[[http://www.uniprot.org/uniprot/FBF2_CAEEL FBF2_CAEEL]] Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression possibly by directly binding to two sites within the gld-3 isoform B 3'-UTR.<ref>PMID:9393998</ref> <ref>PMID:15454534</ref>
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<StructureSection load='3qgb' size='340' side='right'caption='[[3qgb]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3qgb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QGB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QGB FirstGlance]. <br>
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[[3qgb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QGB OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qgb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qgb OCA], [https://pdbe.org/3qgb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qgb RCSB], [https://www.ebi.ac.uk/pdbsum/3qgb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qgb ProSAT]</span></td></tr>
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==Reference==
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</table>
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<ref group="xtra">PMID:021372189</ref><references group="xtra"/><references/>
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== Function ==
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[https://www.uniprot.org/uniprot/FBF2_CAEEL FBF2_CAEEL] Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression possibly by directly binding to two sites within the gld-3 isoform B 3'-UTR.<ref>PMID:9393998</ref> <ref>PMID:15454534</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
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[[Category: Gross, L.]]
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[[Category: Large Structures]]
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[[Category: Hall, T M.T.]]
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[[Category: Gross L]]
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[[Category: Koh, Y Y.]]
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[[Category: Hall TMT]]
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[[Category: Opperman, L.]]
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[[Category: Koh YY]]
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[[Category: Qiu, C.]]
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[[Category: Opperman L]]
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[[Category: Wang, Y.]]
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[[Category: Qiu C]]
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[[Category: Wickens, M.]]
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[[Category: Wang Y]]
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[[Category: Base stacking]]
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[[Category: Wickens M]]
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[[Category: Fbf]]
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[[Category: Fem-3 binding factor]]
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[[Category: Puf]]
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[[Category: Rna binding protein-rna complex]]
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[[Category: Rna-binding specificity]]
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Current revision

Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa

PDB ID 3qgb

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