3phn
From Proteopedia
(Difference between revisions)
m (Protected "3phn" [edit=sysop:move=sysop]) |
|||
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_3phn| PDB=3phn | SCENE= }} | ||
| - | ===Crystal structure of wild-type onconase with resolution 1.46 A=== | ||
| - | == | + | ==Crystal structure of wild-type onconase with resolution 1.46 A== |
| - | [[ | + | <StructureSection load='3phn' size='340' side='right'caption='[[3phn]], [[Resolution|resolution]] 1.46Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3phn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lithobates_pipiens Lithobates pipiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PHN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PHN FirstGlance]. <br> |
| - | [[3phn]] is a 1 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.46Å</td></tr> |
| - | [ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3phn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3phn OCA], [https://pdbe.org/3phn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3phn RCSB], [https://www.ebi.ac.uk/pdbsum/3phn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3phn ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/RNP30_LITPI RNP30_LITPI] Basic protein with antiproliferative/cytotoxic activity against several tumor cell lines in vitro, as well as antitumor in vivo. It exhibits a ribonuclease-like activity against high molecular weight ribosomal RNA. | |
| - | [ | + | __TOC__ |
| - | [ | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Lithobates pipiens]] |
| - | [[Category: | + | [[Category: Kurpiewska K]] |
| - | [[Category: | + | [[Category: Lewinski K]] |
| - | [[Category: | + | [[Category: Loch J]] |
| - | [[Category: | + | [[Category: Ribo M]] |
| - | [[Category: | + | [[Category: Torrent G]] |
| - | [[Category: | + | [[Category: Vilanova M]] |
Current revision
Crystal structure of wild-type onconase with resolution 1.46 A
| |||||||||||
