3q36

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{{STRUCTURE_3q36| PDB=3q36 | SCENE= }}
 
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===Crystal structure of the 4Fe-4S cluster domain of human DNA primase large subunit===
 
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{{ABSTRACT_PUBMED_21346410}}
 
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==Function==
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==Crystal structure of the 4Fe-4S cluster domain of human DNA primase large subunit==
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[[http://www.uniprot.org/uniprot/PRI2_HUMAN PRI2_HUMAN]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
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<StructureSection load='3q36' size='340' side='right'caption='[[3q36]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3q36]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q36 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q36 OCA], [https://pdbe.org/3q36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q36 RCSB], [https://www.ebi.ac.uk/pdbsum/3q36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q36 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PRI2_HUMAN PRI2_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
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==About this Structure==
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==See Also==
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[[3q36]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q36 OCA].
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021346410</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Agarkar, V B.]]
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[[Category: Large Structures]]
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[[Category: Babayeva, N D.]]
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[[Category: Agarkar VB]]
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[[Category: Tahirov, T H.]]
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[[Category: Babayeva ND]]
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[[Category: Dna replication]]
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[[Category: Tahirov TH]]
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[[Category: Dna-binding]]
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[[Category: Dna-directed rna polymerase]]
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[[Category: Iron-sulfur cluster]]
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[[Category: Metal-binding]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Phosphoprotein]]
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[[Category: Pol alpha]]
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[[Category: Polymerase]]
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[[Category: Primase]]
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[[Category: Primosome]]
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[[Category: Transcription]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the 4Fe-4S cluster domain of human DNA primase large subunit

PDB ID 3q36

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