3pnl

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{{STRUCTURE_3pnl| PDB=3pnl | SCENE= }}
 
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===Crystal Structure of E.coli Dha kinase DhaK-DhaL complex===
 
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{{ABSTRACT_PUBMED_21209328}}
 
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==Function==
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==Crystal Structure of E.coli Dha kinase DhaK-DhaL complex==
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[[http://www.uniprot.org/uniprot/DHAK_ECOLI DHAK_ECOLI]] Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. Binds covalently dihydroxyacetone in hemiaminal linkage. Acts also as a corepressor of DhaR by binding to its sensor domain, in the absence of dihydroxyacetone. [[http://www.uniprot.org/uniprot/DHAL_ECOLI DHAL_ECOLI]] ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL-ADP receives a phosphoryl group from DhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sensor domain of DhaR. DhaL-ATP is inactive.
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<StructureSection load='3pnl' size='340' side='right'caption='[[3pnl]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3pnl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PNL FirstGlance]. <br>
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[[3pnl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PNL OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pnl OCA], [https://pdbe.org/3pnl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pnl RCSB], [https://www.ebi.ac.uk/pdbsum/3pnl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pnl ProSAT]</span></td></tr>
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<ref group="xtra">PMID:021209328</ref><references group="xtra"/><references/>
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</table>
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[[Category: Escherichia coli]]
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== Function ==
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[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
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[https://www.uniprot.org/uniprot/DHAK_ECOLI DHAK_ECOLI] Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. Binds covalently dihydroxyacetone in hemiaminal linkage. Acts also as a corepressor of DhaR by binding to its sensor domain, in the absence of dihydroxyacetone.
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[[Category: Cygler, M.]]
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__TOC__
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[[Category: Ekiel, I.]]
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</StructureSection>
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[[Category: Matte, A.]]
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[[Category: Escherichia coli K-12]]
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[[Category: McDonald, L.]]
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[[Category: Large Structures]]
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[[Category: Shi, R.]]
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[[Category: Cygler M]]
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[[Category: Bsgi]]
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[[Category: Ekiel I]]
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[[Category: Dha kinase]]
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[[Category: Matte A]]
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[[Category: Montreal-kingston bacterial structural genomics initiative]]
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[[Category: McDonald L]]
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[[Category: Structural genomic]]
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[[Category: Shi R]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of E.coli Dha kinase DhaK-DhaL complex

PDB ID 3pnl

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