3qrq

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{{STRUCTURE_3qrq| PDB=3qrq | SCENE= }}
 
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===Structure of Thermus Thermophilus Cse3 bound to an RNA representing a pre-cleavage complex===
 
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{{ABSTRACT_PUBMED_21572444}}
 
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==Function==
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==Structure of Thermus Thermophilus Cse3 bound to an RNA representing a pre-cleavage complex==
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[[http://www.uniprot.org/uniprot/Q53WG9_THET8 Q53WG9_THET8]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Processes pre-crRNA into individual crRNA units, but may not actually undergo enzyme turnover, retaining the crRNA product. Generates a 2',3'-cyclic phosphodiester.<ref>PMID:21572442</ref> <ref>PMID:21572444</ref>
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<StructureSection load='3qrq' size='340' side='right'caption='[[3qrq]], [[Resolution|resolution]] 3.19&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3qrq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QRQ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.194&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qrq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrq OCA], [https://pdbe.org/3qrq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qrq RCSB], [https://www.ebi.ac.uk/pdbsum/3qrq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qrq ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAS6_THET8 CAS6_THET8] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). This enzyme processes pre-crRNA into individual crRNA units, but may not actually undergo enzyme turnover, retaining the crRNA product (PubMed:21572442). Generates a 2',3'-cyclic phosphodiester.<ref>PMID:21572442</ref> <ref>PMID:21572444</ref>
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==About this Structure==
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==See Also==
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[[3qrq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRQ OCA].
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*[[CRISPR type I-E (Cascade)|CRISPR type I-E (Cascade)]]
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
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==Reference==
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== References ==
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<ref group="xtra">PMID:021572444</ref><references group="xtra"/><references/>
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<references/>
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[[Category: Thermus thermophilus hb8]]
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__TOC__
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[[Category: E L., Garside.]]
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</StructureSection>
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[[Category: Gesner, E G.]]
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[[Category: Large Structures]]
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[[Category: MacMillan, A M.]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Schellenberg, M J.]]
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[[Category: Garside EL]]
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[[Category: Protein-rna complex]]
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[[Category: Gesner EG]]
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[[Category: Ramp domain]]
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[[Category: MacMillan AM]]
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[[Category: Rna binding protein-rna complex]]
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[[Category: Schellenberg MJ]]

Current revision

Structure of Thermus Thermophilus Cse3 bound to an RNA representing a pre-cleavage complex

PDB ID 3qrq

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