3pr2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:42, 21 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_3pr2| PDB=3pr2 | SCENE= }}
 
-
===Tryptophan synthase indoline quinonoid structure with F9 inhibitor in alpha site===
 
-
{{ABSTRACT_PUBMED_21142052}}
 
-
==Function==
+
==Tryptophan synthase indoline quinonoid structure with F9 inhibitor in alpha site==
-
[[http://www.uniprot.org/uniprot/TRPA_SALTY TRPA_SALTY]] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. [[http://www.uniprot.org/uniprot/TRPB_SALTY TRPB_SALTY]] The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
+
<StructureSection load='3pr2' size='340' side='right'caption='[[3pr2]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==About this Structure==
+
<table><tr><td colspan='2'>[[3pr2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PR2 FirstGlance]. <br>
-
[[3pr2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PR2 OCA].
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7MN:(Z)-N-[(1E)-1-CARBOXY-2-(2,3-DIHYDRO-1H-INDOL-1-YL)ETHYLIDENE]{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHANAMINIUM'>7MN</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=F9F:2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL+DIHYDROGEN+PHOSPHATE'>F9F</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pr2 OCA], [https://pdbe.org/3pr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pr2 RCSB], [https://www.ebi.ac.uk/pdbsum/3pr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pr2 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TRPA_SALTY TRPA_SALTY] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
==See Also==
==See Also==
-
*[[Tryptophan synthase|Tryptophan synthase]]
+
*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:021142052</ref><references group="xtra"/><references/>
+
[[Category: Large Structures]]
-
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
+
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-
[[Category: Tryptophan synthase]]
+
[[Category: Barends TRM]]
-
[[Category: Barends, T R.M.]]
+
[[Category: Chang CA]]
-
[[Category: Chang, C A.]]
+
[[Category: Domratcheva T]]
-
[[Category: Domratcheva, T.]]
+
[[Category: Dunn MF]]
-
[[Category: Dunn, M F.]]
+
[[Category: Elliott DW]]
-
[[Category: Elliott, D W.]]
+
[[Category: Fatmi MQ]]
-
[[Category: Fatmi, M Q.]]
+
[[Category: Lai J]]
-
[[Category: Lai, J.]]
+
[[Category: Mueller LJ]]
-
[[Category: Mueller, L J.]]
+
[[Category: Niks D]]
-
[[Category: Niks, D.]]
+
[[Category: Olsen RA]]
-
[[Category: Olsen, R A.]]
+
[[Category: Schlichting I]]
-
[[Category: Schlichting, I.]]
+
[[Category: Schwarz F]]
-
[[Category: Schwarz, F.]]
+
[[Category: Wang Y]]
-
[[Category: Wang, Y.]]
+
-
[[Category: Alpha-beta barrel]]
+
-
[[Category: Lyase]]
+
-
[[Category: Tim-barrel]]
+
-
[[Category: Tryptophan synthesis]]
+

Current revision

Tryptophan synthase indoline quinonoid structure with F9 inhibitor in alpha site

PDB ID 3pr2

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools