3q91

{{STRUCTURE_3q91| PDB=3q91 | SCENE= }}

===Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)===

==Function==

[[http://www.uniprot.org/uniprot/NUD14_HUMAN NUD14_HUMAN]] Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose.

 

[[3q91]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q91 OCA].

[[Category: UDP-sugar diphosphatase]]

[[Category: Arrowsmith, C H.]]

[[Category: Berg, S Van Der.]]

[[Category: Berglund, H.]]

[[Category: Bountra, C.]]

[[Category: Collins, R.]]

[[Category: Edwards, A M.]]

[[Category: Ekblad, T.]]

[[Category: Flodin, S.]]

[[Category: Flores, A.]]

[[Category: Graslund, S.]]

[[Category: Hammarstrom, M.]]

[[Category: Johansson, I.]]

[[Category: Karlberg, T.]]

[[Category: Kol, S.]]

[[Category: Kotenyova, T.]]

[[Category: Kouznetsova, E.]]

[[Category: Moche, M.]]

[[Category: Nordlund, P.]]

[[Category: Nyman, T.]]

[[Category: Persson, C.]]

[[Category: SGC, Structural Genomics Consortium.]]

[[Category: Schuler, H.]]

[[Category: Schutz, P.]]

[[Category: Siponen, M I.]]

[[Category: Thorsell, A G.]]

[[Category: Tresaugues, L.]]

[[Category: Wahlberg, E.]]

[[Category: Weigelt, J.]]

[[Category: Welin, M.]]

[[Category: Hydrolase]]

[[Category: Structural genomics consortium]]