3psn

{{STRUCTURE_3psn| PDB=3psn | SCENE= }}

===Crystal structure of mouse VPS29 complexed with Mn2+===

==Function==

[[http://www.uniprot.org/uniprot/VPS29_MOUSE VPS29_MOUSE]] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro).

==About this Structure==

[[3psn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lh7 3lh7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSN OCA].

[[Category: Chhabra, S.]]

[[Category: Collins, B.]]

[[Category: Ghai, R.]]

[[Category: Norwood, S.]]

[[Category: Shaw, D.]]

[[Category: Swarbrick, J.]]

[[Category: Valkov, E.]]

[[Category: Vps35]]