3qrr

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{{STRUCTURE_3qrr| PDB=3qrr | SCENE= }}
 
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===Structure of Thermus Thermophilus Cse3 bound to an RNA representing a product complex===
 
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{{ABSTRACT_PUBMED_21572444}}
 
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==Function==
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==Structure of Thermus Thermophilus Cse3 bound to an RNA representing a product complex==
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[[http://www.uniprot.org/uniprot/Q53WG9_THET8 Q53WG9_THET8]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Processes pre-crRNA into individual crRNA units, but may not actually undergo enzyme turnover, retaining the crRNA product. Generates a 2',3'-cyclic phosphodiester.<ref>PMID:21572442</ref> <ref>PMID:21572444</ref>
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<StructureSection load='3qrr' size='340' side='right'caption='[[3qrr]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3qrr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QRR FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.099&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=23G:GUANOSINE-5-PHOSPHATE-2,3-CYCLIC+PHOSPHATE'>23G</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qrr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrr OCA], [https://pdbe.org/3qrr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qrr RCSB], [https://www.ebi.ac.uk/pdbsum/3qrr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qrr ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAS6_THET8 CAS6_THET8] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). This enzyme processes pre-crRNA into individual crRNA units, but may not actually undergo enzyme turnover, retaining the crRNA product (PubMed:21572442). Generates a 2',3'-cyclic phosphodiester.<ref>PMID:21572442</ref> <ref>PMID:21572444</ref>
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==About this Structure==
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==See Also==
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[[3qrr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRR OCA].
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*[[CRISPR type I-E (Cascade)|CRISPR type I-E (Cascade)]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:021572444</ref><references group="xtra"/><references/>
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__TOC__
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[[Category: Thermus thermophilus hb8]]
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</StructureSection>
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[[Category: E L., Garside.]]
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[[Category: Large Structures]]
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[[Category: Gesner, E G.]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: MacMillan, A M.]]
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[[Category: Garside EL]]
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[[Category: Schellenberg, M J.]]
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[[Category: Gesner EG]]
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[[Category: Protein-rna complex]]
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[[Category: MacMillan AM]]
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[[Category: Ramp domain]]
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[[Category: Schellenberg MJ]]
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[[Category: Rna binding protein-rna complex]]
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Current revision

Structure of Thermus Thermophilus Cse3 bound to an RNA representing a product complex

PDB ID 3qrr

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