4geg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:28, 1 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_4geg| PDB=4geg | SCENE= }}
 
-
===Crystal Structure of E.coli MenH Y85F Mutant===
 
-
{{ABSTRACT_PUBMED_23637813}}
 
-
==Function==
+
==Crystal Structure of E.coli MenH Y85F Mutant==
-
[[http://www.uniprot.org/uniprot/MENH_ECOLI MENH_ECOLI]] Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro.<ref>PMID:15808744</ref> <ref>PMID:18284213</ref>
+
<StructureSection load='4geg' size='340' side='right'caption='[[4geg]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==About this Structure==
+
<table><tr><td colspan='2'>[[4geg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GEG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GEG FirstGlance]. <br>
-
[[4geg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GEG OCA].
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
==Reference==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4geg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4geg OCA], [https://pdbe.org/4geg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4geg RCSB], [https://www.ebi.ac.uk/pdbsum/4geg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4geg ProSAT]</span></td></tr>
-
<references group="xtra"/><references/>
+
</table>
-
[[Category: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase]]
+
== Function ==
-
[[Category: Escherichia coli k-12]]
+
[https://www.uniprot.org/uniprot/MENH_ECOLI MENH_ECOLI] Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro.<ref>PMID:15808744</ref> <ref>PMID:18284213</ref>
-
[[Category: Baker, E N.]]
+
== References ==
-
[[Category: Guo, Z.]]
+
<references/>
-
[[Category: Jiang, M.]]
+
__TOC__
-
[[Category: Johnston, J M]]
+
</StructureSection>
-
[[Category: 2-succinyl-6-hydroxy-2]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: 4-cyclohexadiene-1-carboxylate synthase]]
+
[[Category: Large Structures]]
-
[[Category: Alpha beta hydrolase]]
+
[[Category: Baker EN]]
-
[[Category: Lyase]]
+
[[Category: Guo Z]]
-
[[Category: Menaquinone biosynthesis]]
+
[[Category: Jiang M]]
-
[[Category: Menh y85f mutant]]
+
[[Category: Johnston JM]]

Current revision

Crystal Structure of E.coli MenH Y85F Mutant

PDB ID 4geg

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4geg"
Personal tools