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2gk9

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[[Image:2gk9.gif|left|200px]]<br /><applet load="2gk9" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2gk9, resolution 2.8&Aring;" />
 
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'''Human Phosphatidylinositol-4-phosphate 5-kinase, type II, gamma'''<br />
 
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==About this Structure==
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==Human Phosphatidylinositol-4-phosphate 5-kinase, type II, gamma==
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2GK9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Active as [http://en.wikipedia.org/wiki/1-phosphatidylinositol-4-phosphate_5-kinase 1-phosphatidylinositol-4-phosphate 5-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.68 2.7.1.68] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GK9 OCA].
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<StructureSection load='2gk9' size='340' side='right'caption='[[2gk9]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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[[Category: 1-phosphatidylinositol-4-phosphate 5-kinase]]
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2gk9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GK9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GK9 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gk9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gk9 OCA], [https://pdbe.org/2gk9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gk9 RCSB], [https://www.ebi.ac.uk/pdbsum/2gk9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gk9 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PI42C_HUMAN PI42C_HUMAN] May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gk/2gk9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gk9 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C.]]
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[[Category: Arrowsmith C]]
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[[Category: Berg, S Van Den.]]
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[[Category: Berglund H]]
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[[Category: Berglund, H.]]
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[[Category: Collins R]]
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[[Category: Collins, R.]]
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[[Category: Edwards A]]
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[[Category: Edwards, A.]]
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[[Category: Ehn M]]
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[[Category: Ehn, M.]]
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[[Category: Flodin S]]
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[[Category: Flodin, S.]]
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[[Category: Flores A]]
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[[Category: Flores, A.]]
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[[Category: Graslund S]]
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[[Category: Graslund, S.]]
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[[Category: Hallberg BM]]
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[[Category: Hallberg, B M.]]
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[[Category: Hammarstrom M]]
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[[Category: Hammarstrom, M.]]
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[[Category: Hogbom M]]
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[[Category: Hogbom, M.]]
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[[Category: Holmberg-Schiavone L]]
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[[Category: Holmberg-Schiavone, L.]]
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[[Category: Kotenyova T]]
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[[Category: Kotenyova, T.]]
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[[Category: Nilsson-Ehle P]]
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[[Category: Nilsson-Ehle, P.]]
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[[Category: Nordlund P]]
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[[Category: Nordlund, P.]]
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[[Category: Nyman T]]
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[[Category: Nyman, T.]]
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[[Category: Ogg D]]
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[[Category: Ogg, D.]]
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[[Category: Persson C]]
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[[Category: Persson, C.]]
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[[Category: Sagemark J]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Stenmark P]]
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[[Category: Sagemark, J.]]
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[[Category: Sundstrom M]]
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[[Category: Stenmark, P.]]
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[[Category: Thorsell AG]]
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[[Category: Sundstrom, M.]]
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[[Category: Uppenberg J]]
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[[Category: Thorsell, A G.]]
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[[Category: Van Den Berg S]]
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[[Category: Uppenberg, J.]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J.]]
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[[Category: kinase]]
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[[Category: phosphoinositide]]
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[[Category: sgc]]
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[[Category: structural genomics]]
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[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:32:30 2008''
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Current revision

Human Phosphatidylinositol-4-phosphate 5-kinase, type II, gamma

PDB ID 2gk9

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