4fw2

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{{STRUCTURE_4fw2| PDB=4fw2 | SCENE= }}
 
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===Crystal structure of RSV three-domain integrase with disordered N-terminal domain===
 
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{{ABSTRACT_PUBMED_23451105}}
 
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==Function==
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==Crystal structure of RSV three-domain integrase with disordered N-terminal domain==
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[[http://www.uniprot.org/uniprot/POL_RSVP POL_RSVP]] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).
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<StructureSection load='4fw2' size='340' side='right'caption='[[4fw2]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4fw2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rous_sarcoma_virus_-_Prague_C Rous sarcoma virus - Prague C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FW2 FirstGlance]. <br>
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[[4fw2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus_-_prague_c Rous sarcoma virus - prague c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FW2 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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[[Category: Rous sarcoma virus - prague c]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fw2 OCA], [https://pdbe.org/4fw2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fw2 RCSB], [https://www.ebi.ac.uk/pdbsum/4fw2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fw2 ProSAT]</span></td></tr>
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[[Category: Aihara, H.]]
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</table>
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[[Category: Shi, K.]]
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== Function ==
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[[Category: Dna binding protein]]
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[https://www.uniprot.org/uniprot/POL_RSVP POL_RSVP] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Rous sarcoma virus - Prague C]]
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[[Category: Aihara H]]
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[[Category: Shi K]]

Current revision

Crystal structure of RSV three-domain integrase with disordered N-terminal domain

PDB ID 4fw2

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