4fw1
From Proteopedia
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| - | {{STRUCTURE_4fw1| PDB=4fw1 | SCENE= }} | ||
| - | ===Crystal structure of two-domain RSV INTEGRASE covalently linked with DNA=== | ||
| - | {{ABSTRACT_PUBMED_23451105}} | ||
| - | == | + | ==Crystal structure of two-domain RSV INTEGRASE covalently linked with DNA== |
| - | [[http://www.uniprot.org/uniprot/POL_RSVP POL_RSVP | + | <StructureSection load='4fw1' size='340' side='right'caption='[[4fw1]], [[Resolution|resolution]] 1.86Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4fw1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rous_sarcoma_virus_-_Prague_C Rous sarcoma virus - Prague C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FW1 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fw1 OCA], [https://pdbe.org/4fw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fw1 RCSB], [https://www.ebi.ac.uk/pdbsum/4fw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fw1 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/POL_RSVP POL_RSVP] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity). | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Integrase|Integrase]] |
| - | [[Category: Rous sarcoma virus - | + | __TOC__ |
| - | [[Category: Aihara | + | </StructureSection> |
| - | [[Category: Shi | + | [[Category: Large Structures]] |
| - | + | [[Category: Rous sarcoma virus - Prague C]] | |
| + | [[Category: Aihara H]] | ||
| + | [[Category: Shi K]] | ||
Current revision
Crystal structure of two-domain RSV INTEGRASE covalently linked with DNA
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