3thi
From Proteopedia
(Difference between revisions)
m (Protected "3thi" [edit=sysop:move=sysop]) |
|||
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_3thi| PDB=3thi | SCENE= }} | ||
| - | ===THIAMINASE I FROM BACILLUS THIAMINOLYTICUS=== | ||
| - | {{ABSTRACT_PUBMED_9843405}} | ||
| - | == | + | ==THIAMINASE I FROM BACILLUS THIAMINOLYTICUS== |
| - | [[http://www.uniprot.org/uniprot/THI1_PANTH THI1_PANTH | + | <StructureSection load='3thi' size='340' side='right'caption='[[3thi]], [[Resolution|resolution]] 2.00Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3thi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3THI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3THI FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3thi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3thi OCA], [https://pdbe.org/3thi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3thi RCSB], [https://www.ebi.ac.uk/pdbsum/3thi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3thi ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/THI1_PANTH THI1_PANTH] Degrades thiamine by replacing its thiazole moiety with a wide range of nucleophiles. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/th/3thi_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3thi ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Thiaminase|Thiaminase]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Begley | + | [[Category: Begley TP]] |
| - | [[Category: Campobasso | + | [[Category: Campobasso N]] |
| - | [[Category: Ealick | + | [[Category: Ealick SE]] |
| - | + | ||
| - | + | ||
Current revision
THIAMINASE I FROM BACILLUS THIAMINOLYTICUS
| |||||||||||
