This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3qwm

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:35, 20 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_3qwm| PDB=3qwm | SCENE= }}
 
-
===Crystal Structure of GEP100, the plextrin homology domain of IQ motif and SEC7 domain-containing protein 1 isoform a===
 
-
==About this Structure==
+
==Crystal Structure of GEP100, the plextrin homology domain of IQ motif and SEC7 domain-containing protein 1 isoform a==
-
[[3qwm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWM OCA].
+
<StructureSection load='3qwm' size='340' side='right'caption='[[3qwm]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3qwm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QWM FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.39&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwm OCA], [https://pdbe.org/3qwm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qwm RCSB], [https://www.ebi.ac.uk/pdbsum/3qwm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qwm ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/IQEC1_HUMAN IQEC1_HUMAN] In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.<ref>PMID:11226253</ref> <ref>PMID:16461286</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Allerston, C.]]
+
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Allerston C]]
-
[[Category: Bountra, C.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Chaikuad, A.]]
+
[[Category: Bountra C]]
-
[[Category: Delft, F von.]]
+
[[Category: Chaikuad A]]
-
[[Category: Edwards, A.]]
+
[[Category: Edwards A]]
-
[[Category: Feller, S.]]
+
[[Category: Feller S]]
-
[[Category: Felletar, I.]]
+
[[Category: Felletar I]]
-
[[Category: Filippakopoulos, P.]]
+
[[Category: Filippakopoulos P]]
-
[[Category: Janning, M.]]
+
[[Category: Janning M]]
-
[[Category: Knapp, S.]]
+
[[Category: Knapp S]]
-
[[Category: Krojer, T.]]
+
[[Category: Krojer T]]
-
[[Category: Picaud, S.]]
+
[[Category: Picaud S]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Sabe H]]
-
[[Category: Sabe, H.]]
+
[[Category: Weigelt J]]
-
[[Category: Weigelt, J.]]
+
[[Category: Von Delft F]]
-
[[Category: Alpha-catenin]]
+
-
[[Category: Arf1]]
+
-
[[Category: Arf5]]
+
-
[[Category: Arf6]]
+
-
[[Category: Egfr]]
+
-
[[Category: Guanine nucleotide exchange factor]]
+
-
[[Category: Ph domain]]
+
-
[[Category: Sgc]]
+
-
[[Category: Signaling protein]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structural genomics consortium]]
+

Current revision

Crystal Structure of GEP100, the plextrin homology domain of IQ motif and SEC7 domain-containing protein 1 isoform a

PDB ID 3qwm

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3qwm"
Personal tools