This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3rbg
From Proteopedia
(Difference between revisions)
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_3rbg| PDB=3rbg | SCENE= }} | ||
| - | ===Crystal structure analysis of Class-I MHC restricted T-cell associated molecule=== | ||
| - | == | + | ==Crystal structure analysis of Class-I MHC restricted T-cell associated molecule== |
| - | [[3rbg]] is a 4 chain structure with sequence from [ | + | <StructureSection load='3rbg' size='340' side='right'caption='[[3rbg]], [[Resolution|resolution]] 2.30Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3rbg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RBG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RBG FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rbg OCA], [https://pdbe.org/3rbg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rbg RCSB], [https://www.ebi.ac.uk/pdbsum/3rbg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rbg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CRTAM_HUMAN CRTAM_HUMAN] Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.<ref>PMID:15811952</ref> [UniProtKB:Q149L7] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Almo SC]] |
| - | [[Category: | + | [[Category: Fiser A]] |
| - | + | [[Category: Nathenson SG]] | |
| - | [[Category: Nathenson | + | [[Category: Ramagopal UA]] |
| - | [[Category: Ramagopal | + | [[Category: Rubinstein R]] |
| - | [[Category: Rubinstein | + | [[Category: Toro R]] |
| - | [[Category: Toro | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure analysis of Class-I MHC restricted T-cell associated molecule
| |||||||||||
