2gtq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:14, 17 October 2024) (edit) (undo)
 
(17 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2gtq.gif|left|200px]]<br /><applet load="2gtq" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2gtq, resolution 2.05&Aring;" />
 
-
'''Crystal structure of aminopeptidase N from human pathogen Neisseria meningitidis'''<br />
 
-
==About this Structure==
+
==Crystal structure of aminopeptidase N from human pathogen Neisseria meningitidis==
-
2GTQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_mc58 Neisseria meningitidis mc58] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Membrane_alanyl_aminopeptidase Membrane alanyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.2 3.4.11.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTQ OCA].
+
<StructureSection load='2gtq' size='340' side='right'caption='[[2gtq]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2gtq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis_MC58 Neisseria meningitidis MC58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GTQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GTQ FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gtq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gtq OCA], [https://pdbe.org/2gtq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gtq RCSB], [https://www.ebi.ac.uk/pdbsum/2gtq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gtq ProSAT], [https://www.topsan.org/Proteins/MCSG/2gtq TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q9JYV4_NEIMB Q9JYV4_NEIMB]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gt/2gtq_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gtq ConSurf].
 +
<div style="clear:both"></div>
-
==Reference==
+
==See Also==
-
Crystal structure of aminopeptidase N from human pathogen Neisseria meningitidis., Nocek B, Mulligan R, Bargassa M, Collart F, Joachimiak A, Proteins. 2008 Jan 1;70(1):273-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17876832 17876832]
+
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
-
[[Category: Membrane alanyl aminopeptidase]]
+
__TOC__
-
[[Category: Neisseria meningitidis mc58]]
+
</StructureSection>
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Bargassa, M.]]
+
[[Category: Neisseria meningitidis MC58]]
-
[[Category: Joachimiak, A.]]
+
[[Category: Bargassa M]]
-
[[Category: MCSG, Midwest Center for Structural Genomics.]]
+
[[Category: Joachimiak A]]
-
[[Category: Mulligan, R.]]
+
[[Category: Mulligan R]]
-
[[Category: Nocek, B.]]
+
[[Category: Nocek B]]
-
[[Category: SO4]]
+
-
[[Category: ZN]]
+
-
[[Category: alanine aminopeptidase]]
+
-
[[Category: aminopeptidase n]]
+
-
[[Category: hydrolase]]
+
-
[[Category: m1 family peptidases]]
+
-
[[Category: mcsg]]
+
-
[[Category: midwest center for structural genomics]]
+
-
[[Category: protein structure initiative]]
+
-
[[Category: psi-2]]
+
-
[[Category: structural genomics]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:35:16 2008''
+

Current revision

Crystal structure of aminopeptidase N from human pathogen Neisseria meningitidis

PDB ID 2gtq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools