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4if4

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{{STRUCTURE_4if4| PDB=4if4 | SCENE= }}
 
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===Crystal Structure of the Magnesium and beryllofluoride-activated VraR from Staphylococcus aureus===
 
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{{ABSTRACT_PUBMED_23650349}}
 
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==About this Structure==
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==Crystal Structure of the Magnesium and beryllofluoride-activated VraR from Staphylococcus aureus==
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[[4if4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IF4 OCA].
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<StructureSection load='4if4' size='340' side='right'caption='[[4if4]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4if4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IF4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IF4 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4if4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4if4 OCA], [https://pdbe.org/4if4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4if4 RCSB], [https://www.ebi.ac.uk/pdbsum/4if4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4if4 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VRAR_STAAM VRAR_STAAM] Member of the two-component regulatory system VraS/VraR involved in the control of the cell wall peptidoglycan biosynthesis. VraR is overexpressed in strain Mu50, which leads to vancomycin resistance.
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==Reference==
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==See Also==
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<ref group="xtra">PMID:023650349</ref><references group="xtra"/><references/>
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*[[Response regulator 3D structure|Response regulator 3D structure]]
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[[Category: Staphylococcus aureus subsp. aureus mu50]]
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__TOC__
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[[Category: Leonard, P G.]]
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</StructureSection>
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[[Category: Stock, A M.]]
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[[Category: Large Structures]]
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[[Category: Bacterial signalling]]
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[[Category: Staphylococcus aureus subsp. aureus Mu50]]
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[[Category: Dna binding]]
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[[Category: Leonard PG]]
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[[Category: Phosphorylation]]
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[[Category: Stock AM]]
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[[Category: Response regulator]]
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[[Category: Transcription]]
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[[Category: Transcription factor]]
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[[Category: Transcription regulation]]
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[[Category: Two-component system]]
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Current revision

Crystal Structure of the Magnesium and beryllofluoride-activated VraR from Staphylococcus aureus

PDB ID 4if4

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