4l2m
From Proteopedia
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(New page: {{STRUCTURE_4l2m| PDB=4l2m | SCENE= }} ===Crystal structure of the 2/2 hemoglobin from Synechococcus sp. PCC 7002 in the cyanomet state and with covalently attached heme=== ==About t...) |
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| - | {{STRUCTURE_4l2m| PDB=4l2m | SCENE= }} | ||
| - | ===Crystal structure of the 2/2 hemoglobin from Synechococcus sp. PCC 7002 in the cyanomet state and with covalently attached heme=== | ||
| - | == | + | ==Crystal structure of the 2/2 hemoglobin from Synechococcus sp. PCC 7002 in the cyanomet state and with covalently attached heme== |
| - | [[4l2m]] is a 2 chain structure with sequence from [ | + | <StructureSection load='4l2m' size='340' side='right'caption='[[4l2m]], [[Resolution|resolution]] 2.25Å' scene=''> |
| - | + | == Structural highlights == | |
| - | [[ | + | <table><tr><td colspan='2'>[[4l2m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechococcus_sp._PCC_7002 Synechococcus sp. PCC 7002]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L2M FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l2m OCA], [https://pdbe.org/4l2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l2m RCSB], [https://www.ebi.ac.uk/pdbsum/4l2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l2m ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/Q8RT58_PICP2 Q8RT58_PICP2] |
| - | [[Category: | + | <div style="background-color:#fffaf0;"> |
| - | [[Category: | + | == Publication Abstract from PubMed == |
| - | [[Category: | + | The X-ray structures of the hemoglobin from Synechococcus sp. PCC 7002 (GlbN) were solved in the ferric bis-histidine (1.44 A resolution) and cyanide-bound (2.25 A resolution) states with covalently attached heme. The two structures illustrate the conformational changes and cavity opening caused by exogenous ligand binding. They also reveal an unusually distorted heme, ruffled as in c cytochromes. Comparison to the solution structure demonstrates the influence of crystal packing on several structural elements, whereas comparison to GlbN from Synechocystis sp. PCC 6803 shows subtle differences in heme geometries and environment. The new structures will be instrumental in elucidating GlbN reactivity. (c) Proteins 2013;. (c) 2013 Wiley Periodicals, Inc. |
| - | [[Category: | + | |
| + | The 2/2 hemoglobin from the cyanobacterium Synechococcus sp. PCC 7002 with covalently attached heme: Comparison of X-ray and NMR structures.,Wenke BB, Lecomte JT, Heroux A, Schlessman JL Proteins. 2013 Sep 2. doi: 10.1002/prot.24409. PMID:23999883<ref>PMID:23999883</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 4l2m" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synechococcus sp. PCC 7002]] | ||
| + | [[Category: Heroux A]] | ||
| + | [[Category: Lecomte JTJ]] | ||
| + | [[Category: Schlessman JL]] | ||
| + | [[Category: Wenke BB]] | ||
Current revision
Crystal structure of the 2/2 hemoglobin from Synechococcus sp. PCC 7002 in the cyanomet state and with covalently attached heme
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