3q0m
From Proteopedia
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| - | {{STRUCTURE_3q0m| PDB=3q0m | SCENE= }} | ||
| - | ===Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREb=== | ||
| - | {{ABSTRACT_PUBMED_21397187}} | ||
| - | == | + | ==Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREb== |
| - | [[ | + | <StructureSection load='3q0m' size='340' side='right'caption='[[3q0m]], [[Resolution|resolution]] 2.71Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3q0m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q0M FirstGlance]. <br> |
| - | [[3q0m]] is a 4 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.705Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0m OCA], [https://pdbe.org/3q0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q0m RCSB], [https://www.ebi.ac.uk/pdbsum/3q0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q0m ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | < | + | == Function == |
| + | [https://www.uniprot.org/uniprot/PUM1_HUMAN PUM1_HUMAN] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Hall TMT]] |
| - | [[Category: | + | [[Category: Lu G]] |
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Current revision
Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREb
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