3wbr

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m (Protected "3wbr" [edit=sysop:move=sysop])
Current revision (06:46, 3 April 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 3wbr is ON HOLD
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==Crystal structure of carbohydrate recognition domain of Blood Dendritic Cell Antigen-2 (BDCA2) lectin (crystal form-3)==
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<StructureSection load='3wbr' size='340' side='right'caption='[[3wbr]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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Authors: Nagae, M., Yamaguchi, Y.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3wbr]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WBR FirstGlance]. <br>
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Description: Crystal structure of lectin (crystal form-3)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wbr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wbr OCA], [https://pdbe.org/3wbr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wbr RCSB], [https://www.ebi.ac.uk/pdbsum/3wbr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wbr ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CLC4C_HUMAN CLC4C_HUMAN] Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose.<ref>PMID:11748283</ref> <ref>PMID:11031109</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Ikeda A]]
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[[Category: Kitago Y]]
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[[Category: Matsumoto N]]
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[[Category: Nagae M]]
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[[Category: Yamaguchi Y]]
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[[Category: Yamamoto K]]

Current revision

Crystal structure of carbohydrate recognition domain of Blood Dendritic Cell Antigen-2 (BDCA2) lectin (crystal form-3)

PDB ID 3wbr

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