4iy2
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4== | |
| - | + | <StructureSection load='4iy2' size='340' side='right'caption='[[4iy2]], [[Resolution|resolution]] 3.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4iy2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IY2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iy2 OCA], [https://pdbe.org/4iy2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iy2 RCSB], [https://www.ebi.ac.uk/pdbsum/4iy2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iy2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Accardi A]] | ||
| + | [[Category: Corral-Rodriguez MA]] | ||
| + | [[Category: Diercks T]] | ||
| + | [[Category: Encinar JA]] | ||
| + | [[Category: Ereno-Orbea J]] | ||
| + | [[Category: Gomez-Garcia I]] | ||
| + | [[Category: Martinez-Cruz LA]] | ||
| + | [[Category: Muller D]] | ||
| + | [[Category: Oyenarte I]] | ||
| + | [[Category: Spiwok V]] | ||
| + | [[Category: Stuiver M]] | ||
| + | [[Category: Terashima H]] | ||
Current revision
Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
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