4jd6
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of Mycobacterium tuberculosis Eis in complex with coenzyme A and tobramycin== | |
- | + | <StructureSection load='4jd6' size='340' side='right'caption='[[4jd6]], [[Resolution|resolution]] 3.50Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4jd6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JD6 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> | |
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=TOY:TOBRAMYCIN'>TOY</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jd6 OCA], [https://pdbe.org/4jd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jd6 RCSB], [https://www.ebi.ac.uk/pdbsum/4jd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jd6 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
+ | [[Category: Biswas T]] | ||
+ | [[Category: Chen W]] | ||
+ | [[Category: Garneau-Tsodikova S]] | ||
+ | [[Category: Tsodikov OV]] |
Current revision
Crystal structure of Mycobacterium tuberculosis Eis in complex with coenzyme A and tobramycin
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