4ksb
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain== | |
| - | + | <StructureSection load='4ksb' size='340' side='right'caption='[[4ksb]], [[Resolution|resolution]] 3.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ksb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KSB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8001Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ksb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ksb OCA], [https://pdbe.org/4ksb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ksb RCSB], [https://www.ebi.ac.uk/pdbsum/4ksb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ksb ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Caya A]] | ||
| + | [[Category: Chang G]] | ||
| + | [[Category: Cregger C]] | ||
| + | [[Category: Doshi R]] | ||
| + | [[Category: Falson P]] | ||
| + | [[Category: Govaerts C]] | ||
| + | [[Category: Grimard V]] | ||
| + | [[Category: Lee C-W]] | ||
| + | [[Category: Martinez L]] | ||
| + | [[Category: Pardon E]] | ||
| + | [[Category: Steyaert J]] | ||
| + | [[Category: Swartz DJ]] | ||
| + | [[Category: Szewczyk P]] | ||
| + | [[Category: Urbatsch I]] | ||
| + | [[Category: Villaluz M]] | ||
| + | [[Category: Ward A]] | ||
Current revision
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
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Categories: Large Structures | Mus musculus | Caya A | Chang G | Cregger C | Doshi R | Falson P | Govaerts C | Grimard V | Lee C-W | Martinez L | Pardon E | Steyaert J | Swartz DJ | Szewczyk P | Urbatsch I | Villaluz M | Ward A
