4ktp
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of 2-O-alpha-glucosylglycerol phosphorylase in complex with glucose== | |
| - | + | <StructureSection load='4ktp' size='340' side='right'caption='[[4ktp]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ktp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_selenitireducens_MLS10 Bacillus selenitireducens MLS10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KTP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ktp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ktp OCA], [https://pdbe.org/4ktp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ktp RCSB], [https://www.ebi.ac.uk/pdbsum/4ktp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ktp ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GGP_BACIE GGP_BACIE] Catalyzes both the (1) reversible phosphorolysis of 2-O-alpha-D-glucopyranosyl-sn-glycerol (GG) from beta-D-glucose 1-phosphate (betaGlc1P) and glycerol and (2) the hydrolysis of betaGlc1P. the betaGlc1P hydrolysis is a glucosyl-transfer reaction to an acceptor water molecule that produces an anomer-inverted alpha-glucose, not a phosphatase-type reaction. In the absence of glycerol produces alpha-D-glucopyranose and phosphate from beta-D-glucopyranose 1-phosphate.<ref>PMID:24466148</ref> <ref>PMID:24828502</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fushinobu S]] | ||
| + | [[Category: Kitaoka M]] | ||
| + | [[Category: Nakai H]] | ||
| + | [[Category: Nihira T]] | ||
| + | [[Category: Touhara KK]] | ||
Current revision
Crystal structure of 2-O-alpha-glucosylglycerol phosphorylase in complex with glucose
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