4l0o
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure determination of cystathionine gamma-synthase from Helicobacter pylori== | |
| + | <StructureSection load='4l0o' size='340' side='right'caption='[[4l0o]], [[Resolution|resolution]] 2.76Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4l0o]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L0O FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.76Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l0o OCA], [https://pdbe.org/4l0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l0o RCSB], [https://www.ebi.ac.uk/pdbsum/4l0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l0o ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/METB_HELPY METB_HELPY] Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[Cystathionine gamma synthase|Cystathionine gamma synthase]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Helicobacter pylori 26695]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gourinath S]] | ||
| + | [[Category: Rehman SAA]] | ||
| + | [[Category: Tarique KF]] | ||
Current revision
Structure determination of cystathionine gamma-synthase from Helicobacter pylori
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