3aua

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{{STRUCTURE_3aua| PDB=3aua | SCENE= }}
 
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===Crystal structure of the quaternary complex-2 of an isomerase===
 
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{{ABSTRACT_PUBMED_22355528}}
 
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==About this Structure==
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==Crystal structure of the quaternary complex-2 of an isomerase==
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[[3aua]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AUA OCA].
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<StructureSection load='3aua' size='340' side='right'caption='[[3aua]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3aua]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AUA FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=F98:3-[ETHANOYL(HYDROXY)AMINO]PROPYLPHOSPHONIC+ACID'>F98</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aua OCA], [https://pdbe.org/3aua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aua RCSB], [https://www.ebi.ac.uk/pdbsum/3aua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aua ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DXR_PLAFX DXR_PLAFX] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).<ref>PMID:10477522</ref>
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==Reference==
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==See Also==
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<ref group="xtra">PMID:022355528</ref><references group="xtra"/><references/>
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*[[DXP reductoisomerase 3D Structures|DXP reductoisomerase 3D Structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
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[[Category: Kitade, Y.]]
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[[Category: Kitade Y]]
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[[Category: Kusakabe, Y.]]
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[[Category: Kusakabe Y]]
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[[Category: Nakamura, K T.]]
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[[Category: Nakamura KT]]
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[[Category: Nakanishi, M.]]
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[[Category: Nakanishi M]]
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[[Category: Tanaka, N.]]
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[[Category: Tanaka N]]
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[[Category: Umeda, T.]]
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[[Category: Umeda T]]
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[[Category: Isomerase-isomerase inhibitor complex]]
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[[Category: Nadph binding]]
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Crystal structure of the quaternary complex-2 of an isomerase

PDB ID 3aua

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