4dkk

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{{STRUCTURE_4dkk| PDB=4dkk | SCENE= }}
 
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===The X-ray Crystal Structure of the Human STAU1 SSM-'RBD'5 Domain-Swapped Dimer===
 
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{{ABSTRACT_PUBMED_23524536}}
 
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==Function==
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==The X-ray Crystal Structure of the Human STAU1 SSM-'RBD'5 Domain-Swapped Dimer==
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[[http://www.uniprot.org/uniprot/STAU1_HUMAN STAU1_HUMAN]] Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
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<StructureSection load='4dkk' size='340' side='right'caption='[[4dkk]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4dkk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DKK FirstGlance]. <br>
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[[4dkk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKK OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.701&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dkk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dkk OCA], [https://pdbe.org/4dkk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dkk RCSB], [https://www.ebi.ac.uk/pdbsum/4dkk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dkk ProSAT]</span></td></tr>
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<ref group="xtra">PMID:023524536</ref><references group="xtra"/><references/>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/STAU1_HUMAN STAU1_HUMAN] Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Gleghorn, M L.]]
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[[Category: Large Structures]]
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[[Category: Beta sheet]]
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[[Category: Gleghorn ML]]
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[[Category: Dimerization]]
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[[Category: Protein binding]]
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[[Category: Rbd]]
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[[Category: Rna binding protein]]
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[[Category: Swapping-motif]]
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The X-ray Crystal Structure of the Human STAU1 SSM-'RBD'5 Domain-Swapped Dimer

PDB ID 4dkk

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