3ay5
From Proteopedia
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| - | {{STRUCTURE_3ay5| PDB=3ay5 | SCENE= }} | ||
| - | ===Crystal structure of HHM (human homologue of murine maternal Id-like molecule)=== | ||
| - | {{ABSTRACT_PUBMED_22453338}} | ||
| - | == | + | ==Crystal structure of HHM (human homologue of murine maternal Id-like molecule)== |
| - | [[ | + | <StructureSection load='3ay5' size='340' side='right'caption='[[3ay5]], [[Resolution|resolution]] 2.50Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3ay5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AY5 FirstGlance]. <br> |
| - | [[3ay5]] is a 1 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ay5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ay5 OCA], [https://pdbe.org/3ay5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ay5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ay5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ay5 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | < | + | == Function == |
| + | [https://www.uniprot.org/uniprot/CCDB1_HUMAN CCDB1_HUMAN] May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.<ref>PMID:10801854</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Ishitani R]] |
| - | [[Category: | + | [[Category: Nureki O]] |
| - | [[Category: | + | [[Category: Seto A]] |
| - | + | ||
Current revision
Crystal structure of HHM (human homologue of murine maternal Id-like molecule)
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