4gfl

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{{STRUCTURE_4gfl| PDB=4gfl | SCENE= }}
 
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===NO mechanism, slma===
 
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{{ABSTRACT_PUBMED_23754405}}
 
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==Function==
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==NO mechanism, slma==
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[[http://www.uniprot.org/uniprot/SLMA_KLEP3 SLMA_KLEP3]] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity).
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<StructureSection load='4gfl' size='340' side='right'caption='[[4gfl]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4gfl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_342 Klebsiella pneumoniae 342]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GFL FirstGlance]. <br>
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[[4gfl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae_342 Klebsiella pneumoniae 342]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFL OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gfl OCA], [https://pdbe.org/4gfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gfl RCSB], [https://www.ebi.ac.uk/pdbsum/4gfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gfl ProSAT]</span></td></tr>
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==Reference==
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</table>
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<ref group="xtra">PMID:023754405</ref><references group="xtra"/><references/>
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== Function ==
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[https://www.uniprot.org/uniprot/SLMA_KLEP3 SLMA_KLEP3] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity).
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__TOC__
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</StructureSection>
[[Category: Klebsiella pneumoniae 342]]
[[Category: Klebsiella pneumoniae 342]]
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[[Category: Schumacher, M A.]]
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[[Category: Large Structures]]
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[[Category: Cell division]]
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[[Category: Schumacher MA]]
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[[Category: Cytokinesis]]
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[[Category: Dna binding protein]]
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[[Category: Ftsz]]
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[[Category: No]]
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[[Category: Nucleoid occlusion]]
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[[Category: Slma]]
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Current revision

NO mechanism, slma

PDB ID 4gfl

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