4jmr
From Proteopedia
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- | {{STRUCTURE_4jmr| PDB=4jmr | SCENE= }} | ||
- | ===A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid=== | ||
- | {{ABSTRACT_PUBMED_23675305}} | ||
- | == | + | ==A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid== |
- | [[4jmr]] is a 8 chain structure with sequence from [ | + | <StructureSection load='4jmr' size='340' side='right'caption='[[4jmr]], [[Resolution|resolution]] 2.90Å' scene=''> |
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[4jmr]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_foamy_virus Human foamy virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JMR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JMR FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jmr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jmr OCA], [https://pdbe.org/4jmr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jmr RCSB], [https://www.ebi.ac.uk/pdbsum/4jmr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jmr ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/GAG_FOAMV GAG_FOAMV] Involved in capsid formation and genome binding. Shortly after infection, interaction between incoming particle-associated Gag proteins and host dynein allows centrosomal targeting of the viral genome (associated to Gag), prior to nucleus translocation and integration into host genome.<ref>PMID:16160174</ref> <ref>PMID:12857789</ref> | ||
- | == | + | ==See Also== |
- | + | *[[Gag polyprotein 3D structures|Gag polyprotein 3D structures]] | |
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Human foamy virus]] | [[Category: Human foamy virus]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Ball NJ]] |
- | [[Category: | + | [[Category: Flower TG]] |
- | [[Category: | + | [[Category: Goldstone DC]] |
- | [[Category: | + | [[Category: Taylor IA]] |
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Current revision
A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid
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