4g2j

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:25, 1 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_4g2j| PDB=4g2j | SCENE= }}
 
-
===Human pde9 in complex with selective compound===
 
-
{{ABSTRACT_PUBMED_23025719}}
 
-
==Function==
+
==Human pde9 in complex with selective compound==
-
[[http://www.uniprot.org/uniprot/PDE9A_HUMAN PDE9A_HUMAN]] Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.<ref>PMID:18757755</ref>
+
<StructureSection load='4g2j' size='340' side='right'caption='[[4g2j]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4g2j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G2J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G2J FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0WF:1-CYCLOPENTYL-6-[(1R)-1-(3-PHENOXYAZETIDIN-1-YL)ETHYL]-1,5-DIHYDRO-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE'>0WF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g2j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g2j OCA], [https://pdbe.org/4g2j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g2j RCSB], [https://www.ebi.ac.uk/pdbsum/4g2j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g2j ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/PDE9A_HUMAN PDE9A_HUMAN] Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.<ref>PMID:18757755</ref>
-
==About this Structure==
+
==See Also==
-
[[4g2j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G2J OCA].
+
*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:023025719</ref><references group="xtra"/><references/>
+
__TOC__
-
[[Category: 3',5'-cyclic-GMP phosphodiesterase]]
+
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Liu, S.]]
+
[[Category: Large Structures]]
-
[[Category: Cgmp->gmp]]
+
[[Category: Liu S]]
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Phosphodiesterase]]
+

Current revision

Human pde9 in complex with selective compound

PDB ID 4g2j

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4g2j"
Personal tools