3b5z

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{{STRUCTURE_3b5z| PDB=3b5z | SCENE= }}
 
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===Crystal Structure of MsbA from Salmonella typhimurium with ADP Vanadate===
 
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{{ABSTRACT_PUBMED_18024585}}
 
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==Function==
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==Crystal Structure of MsbA from Salmonella typhimurium with ADP Vanadate==
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[[http://www.uniprot.org/uniprot/MSBA_SALTY MSBA_SALTY]] Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
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<StructureSection load='3b5z' size='340' side='right'caption='[[3b5z]], [[Resolution|resolution]] 4.20&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3b5z]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B5Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B5Z FirstGlance]. <br>
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[[3b5z]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B5Z OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=VO4:VANADATE+ION'>VO4</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b5z OCA], [https://pdbe.org/3b5z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b5z RCSB], [https://www.ebi.ac.uk/pdbsum/3b5z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b5z ProSAT]</span></td></tr>
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<ref group="xtra">PMID:018024585</ref><references group="xtra"/><references/>
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</table>
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[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
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== Function ==
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[[Category: Chang, G.]]
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[https://www.uniprot.org/uniprot/MSBA_SALTY MSBA_SALTY] Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
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[[Category: Reyes, C L.]]
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== Evolutionary Conservation ==
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[[Category: Roth, C B.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Ward, A.]]
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Check<jmol>
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[[Category: Yu, J.]]
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<jmolCheckbox>
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[[Category: Abc transporter]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b5/3b5z_consurf.spt"</scriptWhenChecked>
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[[Category: Atp-binding]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Hydrolase]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Inner membrane]]
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</jmolCheckbox>
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[[Category: Lipid flippase]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b5z ConSurf].
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[[Category: Lipid transport]]
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<div style="clear:both"></div>
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[[Category: Membrane]]
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__TOC__
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[[Category: Membrane protein]]
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</StructureSection>
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[[Category: Msba]]
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[[Category: Large Structures]]
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[[Category: Nucleotide-binding]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Transmembrane]]
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[[Category: Chang G]]
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[[Category: Reyes CL]]
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[[Category: Roth CB]]
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[[Category: Ward A]]
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[[Category: Yu J]]

Current revision

Crystal Structure of MsbA from Salmonella typhimurium with ADP Vanadate

PDB ID 3b5z

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