This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4k7f

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:45, 31 August 2022) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_4k7f| PDB=4k7f | SCENE= }}
 
-
===Newly identified epitope V60 from HBV core protein complexed with HLA-A*0201===
 
-
{{ABSTRACT_PUBMED_23678186}}
 
-
==Disease==
+
==Newly identified epitope V60 from HBV core protein complexed with HLA-A*0201==
-
[[http://www.uniprot.org/uniprot/B2MG_HUMAN B2MG_HUMAN]] Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:[http://omim.org/entry/241600 241600]]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.<ref>PMID:16549777</ref> Note=Beta-2-microglobulin may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. Persistently high beta(2)-microglobulin serum levels lead to amyloidosis in patients on long-term hemodialysis.<ref>PMID:3532124</ref> <ref>PMID:1336137</ref> <ref>PMID:7554280</ref> <ref>PMID:4586824</ref> <ref>PMID:8084451</ref> <ref>PMID:12119416</ref> <ref>PMID:12796775</ref> <ref>PMID:16901902</ref> <ref>PMID:16491088</ref> <ref>PMID:17646174</ref> <ref>PMID:18835253</ref> <ref>PMID:18395224</ref> <ref>PMID:19284997</ref>
+
<StructureSection load='4k7f' size='340' side='right'caption='[[4k7f]]' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K7F FirstGlance]. <br>
 +
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k7f OCA], [https://pdbe.org/4k7f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k7f RCSB], [https://www.ebi.ac.uk/pdbsum/4k7f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k7f ProSAT]</span></td></tr>
 +
</table>
-
==Function==
+
==See Also==
-
[[http://www.uniprot.org/uniprot/1A02_HUMAN 1A02_HUMAN]] Involved in the presentation of foreign antigens to the immune system. [[http://www.uniprot.org/uniprot/B2MG_HUMAN B2MG_HUMAN]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
+
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
[[4k7f]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7F OCA].
+
[[Category: Large Structures]]
-
 
+
[[Category: Meng SD]]
-
==Reference==
+
[[Category: Qi JX]]
-
<ref group="xtra">PMID:023678186</ref><references group="xtra"/><references/>
+
[[Category: Wu Y]]
-
[[Category: Homo sapiens]]
+
[[Category: Zhang Y]]
-
[[Category: Meng, S D.]]
+
-
[[Category: Qi, J X.]]
+
-
[[Category: Wu, Y.]]
+
-
[[Category: Zhang, Y.]]
+
-
[[Category: Disease mutation]]
+
-
[[Category: Host-virus interaction]]
+
-
[[Category: Ig-like domain]]
+
-
[[Category: Immune response]]
+
-
[[Category: Immune system]]
+
-
[[Category: Membrane glycoprotein]]
+
-
[[Category: Tcr]]
+
-
[[Category: Viral capsid protein]]
+
-
[[Category: Viral replication]]
+

Current revision

Newly identified epitope V60 from HBV core protein complexed with HLA-A*0201

PDB ID 4k7f

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4k7f"
Personal tools