4k1c

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{{STRUCTURE_4k1c| PDB=4k1c | SCENE= }}
 
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===VCX1 Calcium/Proton Exchanger===
 
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{{ABSTRACT_PUBMED_23685453}}
 
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==Function==
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==VCX1 Calcium/Proton Exchanger==
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[[http://www.uniprot.org/uniprot/VCX1_YEAST VCX1_YEAST]] Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.<ref>PMID:8668190</ref> <ref>PMID:8628289</ref>
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<StructureSection load='4k1c' size='340' side='right'caption='[[4k1c]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4k1c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K1C FirstGlance]. <br>
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[[4k1c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K1C OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k1c OCA], [https://pdbe.org/4k1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k1c RCSB], [https://www.ebi.ac.uk/pdbsum/4k1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k1c ProSAT]</span></td></tr>
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<ref group="xtra">PMID:023685453</ref><references group="xtra"/><references/>
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</table>
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[[Category: Saccharomyces cerevisiae s288c]]
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== Function ==
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[[Category: CSMP, Center for Structures of Membrane Proteins.]]
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[https://www.uniprot.org/uniprot/VCX1_YEAST VCX1_YEAST] Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.<ref>PMID:8668190</ref> <ref>PMID:8628289</ref>
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[[Category: Pedersen, B P.]]
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== References ==
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[[Category: Stroud, R M.]]
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<references/>
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[[Category: Waight, A B.]]
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__TOC__
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[[Category: Calcium transport]]
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</StructureSection>
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[[Category: Center for structures of membrane protein]]
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[[Category: Large Structures]]
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[[Category: Csmp]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Membrane protein cax ncx nckx]]
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[[Category: Pedersen BP]]
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[[Category: Membrane protein-metal transport complex]]
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[[Category: Stroud RM]]
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[[Category: Protein structure initiative]]
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[[Category: Waight AB]]
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[[Category: Psi-biology]]
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[[Category: Structural genomic]]
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[[Category: Transport protein]]
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[[Category: Vacuole]]
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Current revision

VCX1 Calcium/Proton Exchanger

PDB ID 4k1c

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