3vyp

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{{STRUCTURE_3vyp| PDB=3vyp | SCENE= }}
 
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===Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase LdtMt2-N140 adduct with meropenem===
 
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==About this Structure==
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==Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase LdtMt2-N140 adduct with meropenem==
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[[3vyp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_caccae Bacteroides caccae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VYP OCA].
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<StructureSection load='3vyp' size='340' side='right'caption='[[3vyp]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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== Structural highlights ==
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==Reference==
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<table><tr><td colspan='2'>[[3vyp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VYP FirstGlance]. <br>
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<ref group="xtra">PMID:023588382</ref><references group="xtra"/><references/>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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[[Category: Bacteroides caccae]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MXR:(2S,3R,4S)-4-{[(3S,5R)-5-(DIMETHYLCARBAMOYL)PYRROLIDIN-3-YL]SULFANYL}-2-[(2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL]-3-METHYL-3,4-DIHYDRO-2H-PYRROLE-5-CARBOXYLIC+ACID'>MXR</scene></td></tr>
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[[Category: Peptidyltransferase]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vyp OCA], [https://pdbe.org/3vyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vyp RCSB], [https://www.ebi.ac.uk/pdbsum/3vyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vyp ProSAT]</span></td></tr>
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[[Category: Bi, L J.]]
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</table>
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[[Category: Li, D F.]]
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== Function ==
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[[Category: Li, W J.]]
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[https://www.uniprot.org/uniprot/LDT2_MYCTU LDT2_MYCTU] Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems.<ref>PMID:24041897</ref>
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[[Category: Wang, D C.]]
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== References ==
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[[Category: Beta barrel]]
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<references/>
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[[Category: Beta-lactam binding]]
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__TOC__
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[[Category: D-transpeptidase]]
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</StructureSection>
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[[Category: Transferase]]
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[[Category: Large Structures]]
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[[Category: Ykud domain]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Bi LJ]]
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[[Category: Li DF]]
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[[Category: Li WJ]]
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[[Category: Wang DC]]

Current revision

Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase LdtMt2-N140 adduct with meropenem

PDB ID 3vyp

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