4kx3

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{{STRUCTURE_4kx3| PDB=4kx3 | SCENE= }}
 
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===Structure of murine cytosolic 5'-nucleotidase III complexed with thymidine monophosphate===
 
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==Function==
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==Structure of murine cytosolic 5'-nucleotidase III complexed with thymidine monophosphate==
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[[http://www.uniprot.org/uniprot/5NT3_MOUSE 5NT3_MOUSE]] Can act both as nucleotidase and as phosphotransferase (By similarity).
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<StructureSection load='4kx3' size='340' side='right'caption='[[4kx3]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4kx3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KX3 FirstGlance]. <br>
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[[4kx3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KX3 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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[[Category: 5'-nucleotidase]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TMP:THYMIDINE-5-PHOSPHATE'>TMP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kx3 OCA], [https://pdbe.org/4kx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kx3 RCSB], [https://www.ebi.ac.uk/pdbsum/4kx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kx3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/5NT3A_MOUSE 5NT3A_MOUSE] Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP). CMP seems to be the preferred substrate.[UniProtKB:Q9H0P0]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Bingman, C A.]]
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[[Category: Bingman CA]]
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[[Category: Bitto, E.]]
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[[Category: Bitto E]]
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[[Category: Grobosky, C L.]]
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[[Category: Grobosky CL]]
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[[Category: Cytosolic 5'-nucleotidase iii]]
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[[Category: Had superfamily]]
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[[Category: Hydrolase]]
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[[Category: Nucleotidase]]
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[[Category: P5n-1]]
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[[Category: Substrate complex]]
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[[Category: Umph-1]]
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Current revision

Structure of murine cytosolic 5'-nucleotidase III complexed with thymidine monophosphate

PDB ID 4kx3

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