2hlz

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[[Image:2hlz.gif|left|200px]]<br /><applet load="2hlz" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2hlz, resolution 1.850&Aring;" />
 
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'''Crystal Structure of human ketohexokinase (CASP Target)'''<br />
 
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==Disease==
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==Crystal Structure of human ketohexokinase==
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Known disease associated with this structure: Fructosuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=229800 229800]]
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<StructureSection load='2hlz' size='340' side='right'caption='[[2hlz]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2hlz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HLZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HLZ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hlz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hlz OCA], [https://pdbe.org/2hlz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hlz RCSB], [https://www.ebi.ac.uk/pdbsum/2hlz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hlz ProSAT]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/2hlz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hlz ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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2HLZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=UNX:'>UNX</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Ketohexokinase Ketohexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.3 2.7.1.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HLZ OCA].
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*[[Ketohexokinase|Ketohexokinase]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Ketohexokinase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Arrowsmith CH]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Bochkarev A]]
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[[Category: Bochkarev, A.]]
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[[Category: Edwards AM]]
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[[Category: Edwards, A M.]]
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[[Category: Landry R]]
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[[Category: Landry, R.]]
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[[Category: Nedyalkova L]]
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[[Category: Nedyalkova, L.]]
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[[Category: Park H]]
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[[Category: Park, H.]]
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[[Category: Rabeh WM]]
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[[Category: Rabeh, W M.]]
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[[Category: Sundstrom M]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Tempel W]]
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[[Category: Sundstrom, M.]]
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[[Category: Weigelt J]]
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[[Category: Tempel, W.]]
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[[Category: Weigelt, J.]]
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[[Category: UNX]]
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[[Category: creatine kinase]]
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[[Category: fructokinase]]
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[[Category: isoform a]]
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[[Category: non-protein kinase]]
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[[Category: sgc]]
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[[Category: structural genomics]]
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[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:43:14 2008''
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Current revision

Crystal Structure of human ketohexokinase

PDB ID 2hlz

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