4gzd

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{{STRUCTURE_4gzd| PDB=4gzd | SCENE= }}
 
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===Crystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118Q===
 
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{{ABSTRACT_PUBMED_23553749}}
 
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==Function==
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==Crystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118Q==
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[[http://www.uniprot.org/uniprot/ENT2_YEAST ENT2_YEAST]] Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.<ref>PMID:10449404</ref>
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<StructureSection load='4gzd' size='340' side='right'caption='[[4gzd]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4gzd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GZD FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gzd OCA], [https://pdbe.org/4gzd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gzd RCSB], [https://www.ebi.ac.uk/pdbsum/4gzd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gzd ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ENT2_YEAST ENT2_YEAST] Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.<ref>PMID:10449404</ref>
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==About this Structure==
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==See Also==
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[[4gzd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GZD OCA].
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*[[Epsin|Epsin]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:023553749</ref><references group="xtra"/><references/>
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__TOC__
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[[Category: Saccharomyces cerevisiae s288c]]
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</StructureSection>
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[[Category: Costakes, G T.]]
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[[Category: Large Structures]]
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[[Category: Stauffacher, C V.]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Endocytosis]]
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[[Category: Costakes GT]]
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[[Category: Enth]]
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[[Category: Stauffacher CV]]
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[[Category: Lipid binding protein]]
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Current revision

Crystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118Q

PDB ID 4gzd

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