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3s3j

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{{STRUCTURE_3s3j| PDB=3s3j | SCENE= }}
 
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===Transglutaminase 2 in complex with a novel inhibitor===
 
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==Function==
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==Transglutaminase 2 in complex with a novel inhibitor==
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[[http://www.uniprot.org/uniprot/TGM2_HUMAN TGM2_HUMAN]] Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
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<StructureSection load='3s3j' size='340' side='right'caption='[[3s3j]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3s3j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S3J FirstGlance]. <br>
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[[3s3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S3J OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=02Y:6-DIAZONIO-5-OXO-L-NORLEUCINE'>02Y</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PHQ:BENZYL+CHLOROCARBONATE'>PHQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s3j OCA], [https://pdbe.org/3s3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s3j RCSB], [https://www.ebi.ac.uk/pdbsum/3s3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s3j ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TGM2_HUMAN TGM2_HUMAN] Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein-glutamine gamma-glutamyltransferase]]
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[[Category: Large Structures]]
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[[Category: Heine, A.]]
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[[Category: Synthetic construct]]
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[[Category: Klebe, G.]]
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[[Category: Heine A]]
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[[Category: Lindemann, I.]]
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[[Category: Klebe G]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Lindemann I]]
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[[Category: Transglutaminase]]
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Current revision

Transglutaminase 2 in complex with a novel inhibitor

PDB ID 3s3j

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