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4dcn

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{{STRUCTURE_4dcn| PDB=4dcn | SCENE= }}
 
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===Crystal Structure Analysis of the Arfaptin2 BAR domain in Complex with ARL1===
 
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{{ABSTRACT_PUBMED_22679020}}
 
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==Function==
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==Crystal Structure Analysis of the Arfaptin2 BAR domain in Complex with ARL1==
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[[http://www.uniprot.org/uniprot/ARL1_HUMAN ARL1_HUMAN]] GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus.<ref>PMID:9624189</ref> [[http://www.uniprot.org/uniprot/ARFP2_HUMAN ARFP2_HUMAN]] Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling.
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<StructureSection load='4dcn' size='340' side='right'caption='[[4dcn]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4dcn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DCN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DCN FirstGlance]. <br>
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[[4dcn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DCN OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.01&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dcn OCA], [https://pdbe.org/4dcn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dcn RCSB], [https://www.ebi.ac.uk/pdbsum/4dcn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dcn ProSAT]</span></td></tr>
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<ref group="xtra">PMID:022679020</ref><references group="xtra"/><references/>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ARL1_HUMAN ARL1_HUMAN] GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus.<ref>PMID:9624189</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Kato, R.]]
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[[Category: Large Structures]]
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[[Category: Kawasaki, M.]]
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[[Category: Kato R]]
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[[Category: Nakamura, K.]]
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[[Category: Kawasaki M]]
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[[Category: Wakatsuki, S.]]
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[[Category: Nakamura K]]
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[[Category: Xie, Y.]]
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[[Category: Wakatsuki S]]
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[[Category: Bar domain]]
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[[Category: Xie Y]]
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[[Category: Membrane deformation]]
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[[Category: Protein binding-signaling protein complex]]
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[[Category: Small gtpase effector complex]]
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Current revision

Crystal Structure Analysis of the Arfaptin2 BAR domain in Complex with ARL1

PDB ID 4dcn

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