2r2y
From Proteopedia
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| - | {{STRUCTURE_2r2y| PDB=2r2y | SCENE= }} | ||
| - | ===Crystal structure of the proteasomal Rpn13 PRU-domain=== | ||
| - | {{ABSTRACT_PUBMED_18497827}} | ||
| - | == | + | ==Crystal structure of the proteasomal Rpn13 PRU-domain== |
| - | [[http://www.uniprot.org/uniprot/ADRM1_MOUSE ADRM1_MOUSE | + | <StructureSection load='2r2y' size='340' side='right'caption='[[2r2y]], [[Resolution|resolution]] 1.70Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[2r2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R2Y FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r2y OCA], [https://pdbe.org/2r2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r2y RCSB], [https://www.ebi.ac.uk/pdbsum/2r2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r2y ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | < | + | == Function == |
| + | [https://www.uniprot.org/uniprot/ADRM1_MOUSE ADRM1_MOUSE] Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity.<ref>PMID:15819879</ref> <ref>PMID:18497827</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r2/2r2y_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r2y ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Dikic | + | [[Category: Dikic I]] |
| - | [[Category: Finley | + | [[Category: Finley D]] |
| - | [[Category: Groll | + | [[Category: Groll M]] |
| - | [[Category: Walters | + | [[Category: Walters K]] |
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Current revision
Crystal structure of the proteasomal Rpn13 PRU-domain
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