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4k43
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of actin in complex with synthetic AplC tail analogue GC04 [N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-dimethoxy-11-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-5,9-dimethyl-6-oxododeca-1,7-dien-1-yl}-N-methylformamide]== | |
| + | <StructureSection load='4k43' size='340' side='right'caption='[[4k43]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4k43]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K43 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PO:N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-DIMETHOXY-11-[(2S,4S,5S)-2-(4-METHOXYPHENYL)-5-METHYL-1,3-DIOXAN-4-YL]-5,9-DIMETHYL-6-OXODODECA-1,7-DIEN-1-YL}-N-METHYLFORMAMIDE'>1PO</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k43 OCA], [https://pdbe.org/4k43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k43 RCSB], [https://www.ebi.ac.uk/pdbsum/4k43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k43 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | ||
| - | + | ==See Also== | |
| - | + | *[[Actin 3D structures|Actin 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Oryctolagus cuniculus]] | ||
| + | [[Category: Adams PD]] | ||
| + | [[Category: Cecere G]] | ||
| + | [[Category: Fink SJ]] | ||
| + | [[Category: Marriott G]] | ||
| + | [[Category: Moriarty NW]] | ||
| + | [[Category: Paterson I]] | ||
| + | [[Category: Pereira JH]] | ||
| + | [[Category: Petchprayoon C]] | ||
Current revision
Crystal structure of actin in complex with synthetic AplC tail analogue GC04 [N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-dimethoxy-11-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-5,9-dimethyl-6-oxododeca-1,7-dien-1-yl}-N-methylformamide]
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