2hy3

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[[Image:2hy3.gif|left|200px]]<br /><applet load="2hy3" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2hy3, resolution 2.60&Aring;" />
 
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'''Crystal structure of the human tyrosine receptor phosphate gamma in complex with vanadate'''<br />
 
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==Disease==
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==Crystal structure of the human tyrosine receptor phosphate gamma in complex with vanadate==
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Known disease associated with this structure: Colon cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600079 600079]]
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<StructureSection load='2hy3' size='340' side='right'caption='[[2hy3]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HY3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HY3 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hy3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hy3 OCA], [https://pdbe.org/2hy3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hy3 RCSB], [https://www.ebi.ac.uk/pdbsum/2hy3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hy3 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2hy3 TOPSAN]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hy/2hy3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hy3 ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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2HY3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=VO4:'>VO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HY3 OCA].
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*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
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[[Category: Homo sapiens]]
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__TOC__
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[[Category: Protein-tyrosine-phosphatase]]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Bera, A.]]
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[[Category: Bera A]]
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[[Category: Burley, S K.]]
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[[Category: Burley SK]]
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[[Category: Freeman, J C.]]
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[[Category: Freeman JC]]
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[[Category: Jin, X.]]
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[[Category: Jin X]]
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[[Category: Min, T.]]
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[[Category: Min T]]
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[[Category: Mu, H.]]
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[[Category: Mu H]]
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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[[Category: Reyes C]]
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[[Category: Reyes, C.]]
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[[Category: Sauder JM]]
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[[Category: Sauder, J M.]]
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[[Category: Shapiro L]]
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[[Category: Shapiro, L.]]
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[[Category: Smith D]]
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[[Category: Smith, D.]]
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[[Category: Wasserman SR]]
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[[Category: Wasserman, S R.]]
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[[Category: VO4]]
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[[Category: new york structural genomix research consortium]]
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[[Category: nysgxrc]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomics]]
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[[Category: twisted mixed beta-sheets flanked by {alpha}-helices]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:47:02 2008''
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Current revision

Crystal structure of the human tyrosine receptor phosphate gamma in complex with vanadate

PDB ID 2hy3

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