This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
CD69
From Proteopedia
(Difference between revisions)
(New page: <StructureSection load='3hup' size='350' side='right' caption='Structure of human CD69 C-type lectin-like domain (PDB entry 3hup)' scene=''> '''CD69''' ('''Cluster of Differentiat...) |
|||
| (8 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | + | <StructureSection load='3hup' size='350' side='right' caption='Structure of human CD69 C-type lectin-like domain dimer complex with Cl- (green) and Na+ (purple) ions (PDB entry [[3hup]])' scene='55/552187/Cv/1'> | |
| - | <StructureSection load='3hup' size='350' side='right' caption='Structure of human CD69 C-type lectin-like domain (PDB entry [[3hup]])' scene=''> | + | |
| - | '''CD69''' ('''Cluster of Differentiation 69''') is a human transmembrane calcium-dependent lectin protein. CD69 functions as a signal-transmitting receptor in lymphocytes natural killer cells and platelets. CD69 expression is induced upon activation of T-cell lymphocytes. | + | '''CD69''' ('''Cluster of Differentiation 69''') is a human transmembrane calcium-dependent lectin protein. CD69 functions as a signal-transmitting receptor in lymphocytes natural killer cells and platelets. CD69 expression is induced upon activation of T-cell lymphocytes. <ref>PMID:11101293</ref> <scene name='55/552187/Cv/3'>Na ion coordination site</scene> of CD69 C-type lectin-like domain dimer complex.<ref>PMID:20054122</ref> Water molecules are shown as red spheres. |
| - | + | </StructureSection> | |
==3D structures of CD69== | ==3D structures of CD69== | ||
| Line 9: | Line 8: | ||
[[1e87]], [[1e8i]], [[1fm5]], [[3cck]], [[3hup]] – hCD69 C-type lectin-like domain – human <br /> | [[1e87]], [[1e8i]], [[1fm5]], [[3cck]], [[3hup]] – hCD69 C-type lectin-like domain – human <br /> | ||
| + | == References == | ||
| + | <references/> | ||
| + | [[Category: Topic Page]] | ||
Current revision
| |||||||||||
3D structures of CD69
Updated on 11-February-2019
1e87, 1e8i, 1fm5, 3cck, 3hup – hCD69 C-type lectin-like domain – human
References
- ↑ Natarajan K, Sawicki MW, Margulies DH, Mariuzza RA. Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells. Biochemistry. 2000 Dec 5;39(48):14779-86. PMID:11101293
- ↑ Kolenko P, Skalova T, Vanek O, Stepankova A, Duskova J, Hasek J, Bezouska K, Dohnalek J. The high-resolution structure of the extracellular domain of human CD69 using a novel polymer. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Dec 1;65(Pt, 12):1258-60. Epub 2009 Nov 27. PMID:20054122 doi:10.1107/S1744309109043152
