1e5g
From Proteopedia
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| - | {{STRUCTURE_1e5g| PDB=1e5g | SCENE= }} | ||
| - | ===Solution structure of central CP module pair of a pox virus complement inhibitor=== | ||
| - | {{ABSTRACT_PUBMED_11243823}} | ||
| - | == | + | ==Solution structure of central CP module pair of a pox virus complement inhibitor== |
| - | [[ | + | <StructureSection load='1e5g' size='340' side='right'caption='[[1e5g]]' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[1e5g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Copenhagen Vaccinia virus Copenhagen]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E5G FirstGlance]. <br> |
| - | [[1e5g]] is a 1 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e5g OCA], [https://pdbe.org/1e5g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e5g RCSB], [https://www.ebi.ac.uk/pdbsum/1e5g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e5g ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | < | + | == Function == |
| - | [[Category: Vaccinia virus | + | [https://www.uniprot.org/uniprot/VCP_VACCC VCP_VACCC] Serves to protect the virus against complement attack by inhibiting both classical and alternative pathways of complement activation. Binds C3b and C4b. |
| - | [[Category: Barlow | + | == Evolutionary Conservation == |
| - | [[Category: Bromek | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[Category: Henderson | + | Check<jmol> |
| - | [[Category: Mullin | + | <jmolCheckbox> |
| - | [[Category: Smith | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e5/1e5g_consurf.spt"</scriptWhenChecked> |
| - | [[Category: Uhrin | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e5g ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Vaccinia virus Copenhagen]] | ||
| + | [[Category: Barlow PN]] | ||
| + | [[Category: Bromek K]] | ||
| + | [[Category: Henderson CE]] | ||
| + | [[Category: Mullin NP]] | ||
| + | [[Category: Smith BO]] | ||
| + | [[Category: Uhrin D]] | ||
Current revision
Solution structure of central CP module pair of a pox virus complement inhibitor
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