4lc2
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the bromodomain of human BRPF1B== | |
| + | <StructureSection load='4lc2' size='340' side='right'caption='[[4lc2]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4lc2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LC2 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lc2 OCA], [https://pdbe.org/4lc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lc2 RCSB], [https://www.ebi.ac.uk/pdbsum/4lc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lc2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Peregrin|Peregrin]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Filippakopoulos P]] | ||
| + | [[Category: Knapp S]] | ||
| + | [[Category: Nunez-Alonso G]] | ||
| + | [[Category: Picaud S]] | ||
| + | [[Category: Savitsky P]] | ||
| + | [[Category: Tallant C]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Crystal structure of the bromodomain of human BRPF1B
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